1H-Pyrazole-1-propanoic acid, 3,5-dimethyl-, hydrazide - Names and Identifiers
1H-Pyrazole-1-propanoic acid, 3,5-dimethyl-, hydrazide - Physico-chemical Properties
Molecular Formula | C8H14N4O
|
Molar Mass | 182.22 |
Density | 1.25±0.1 g/cm3(Predicted) |
Boling Point | 400.9±33.0 °C(Predicted) |
pKa | 12.90±0.35(Predicted) |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD01954426 |
1H-Pyrazole-1-propanoic acid, 3,5-dimethyl-, hydrazide - Introduction
3-(3,) propanohydrazide, chemical formula is C8H14N4O. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White solid
-Melting Point: 136-139°C
-Molecular weight: 186.23g/mol
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dimethyl sulfoxide
Use:
- 3-(3,) propanohydrazide is an important pharmaceutical intermediate and organic synthetic reagent.
-It is often used in the preparation of biologically active compounds, such as anti-tumor drugs, anti-inflammatory drugs, etc.
Preparation Method:
- 3-(3,) The preparation method of propanohydrazide is more complicated, and a commonly used method is obtained by reaction. The specific steps are as follows:
1. First, 3,5-dimethylpyrazole is reacted with acetone in the presence of cuprous chloride to produce 3-(3,5-dimethyl-1H-pyrazol-1-yl) acetone.
2. Then, 3-(3,5-dimethyl-pyrazol-1-yl) acetone is reacted with hydrazine to generate 3-(3, pyridine) 1H propanohydrazide.
Safety Information:
- 3-(3, propanohydrazide) No particularly serious safety risk has been reported. However, as a chemical substance, it still needs to be handled carefully and strictly follow laboratory safety procedures.
-Wear appropriate protective equipment, such as lab gloves, safety glasses and protective clothing, when in use.
-Avoid inhaling the dust of the substance or contact with the skin. If accidental contact or inhalation occurs, please clean the affected area in time or seek medical assistance.
-Store the compound in proper handling and storage.
Last Update:2024-04-09 21:01:54